Patient Focussed Drug Development – Listening to The Patient’s Voice
Gone are the days when patients were merely participants in clinical trials. Today, integrating the patient’s perspective about their diagnosis and treatment experience with reference to the disease plays an important role in developing patient-focused treatment. Developing patient-focused treatment involves prioritizing current unmet needs in a particular disease condition, designing patient-centric trials, and utilizing patient-appropriate […]
Good Publication Practice 2022: An Insight
What are good publication practice (GPP) guidelines? Transparency and accountability have become high priorities for the publication of company-sponsored research. Ethical publication planning should therefore ensure that the design and results of clinical trials and other biomedical research studies are reported accurately and promptly and transparently. GPP guidelines provide recommendations regarding the publication of research […]
Dry Eye Disease – Let’s Keep The Management “Piping Up”
Dry Eye Disease (DED) is one of the most common eye disorders worldwide. It is a multifactorial disease of tears and the ocular surface broadly due to reduced production or increased evaporation of tears, both of which are necessary for good vision, leading to the following: symptoms of discomfort, visual disturbance, tear film instability, […]
Systemic Sclerosis: A Rare Condition Requiring Patient-centric Treatment
Introduction:Systemic sclerosis (SSc) or scleroderma is a rare connective tissue disorder with unknown pathogenesis. Complex interactions between genetic and environmental factors, however, are believed to trigger its development. Pathophysiology:Although the exact cause remains unknown, SSc is characterized by the following pathogenic triad: vasculopathy, inflammation, and fibrosis. Thus, SSc is an autoimmune, progressive, generalized disorder that […]
Allogeneic PBSCT: A New Ray of Hope in Multiple Malignant and Non-malignant diseases
Background:Since their initial introduction in the ’80s, peripheral blood stem cells (PBSCs) have gained momentum as a source of stem cells. Over a period, PBSCs mobilized from the bone marrow through cytokine treatment and collected by apheresis have come to account for the majority of hematopoietic stem cell transplants (HSCTs). Compared to bone marrow stem […]
Esophageal Squamous Cell Carcinoma: Traditional Treatments versus Immunotherapy-based Combination Treatments
Esophageal Squamous Cell Carcinoma (ESCC):ESCC develops in the thin, flat cells lining the inside of the esophagus. This cancer is frequently found in the upper and middle parts of the esophagus, but can occur anywhere along the esophagus. Globally, it is the most common form of esophageal cancer, and, in the East, it continues to […]
Atopic Dermatitis: Old Disease, Newer Therapies
Atopic dermatitis (AD), commonly referred to as eczema, is a chronic, relapsing disease characterized by skin that is dry, itchy, inflamed, and prone to infection. It ranks 15th among all nonfatal diseases globally and carries the highest disease burden. Although the cause of AD is unknown, the following factors are associated with it: human genetic […]
Plain Language Summary of Publications
A plain language summary (PLS) is a concise synopsis containing key take-home messages from a piece of research in a manner that is easily understood by lay people, including patients and the general public. Although lay audiences are interested in medical developments, the scholarly language and terminologies used in medical journals can limit their understanding […]
